Microbial Genetics – Section 1

1. In the time since E. coli and Salmonella diverged evolutionarily

A. there has been little change in either genome
B. E. coli has acquired many genes via horizontal transfer
C. E, coli has lost approximately 50% of its genome
D. none of these

Correct Answer: C. E, coli has lost approximately 50% of its genome

2. Which of the following theory is supported by the genomic sequence of the obligate intracellular parasite Rickettsia prowazekii ?

A. Parasitic bacteria have very large genomes
B. Parasites have a definite genomic sequence similar to viruses
C. Mitochondria have evolved from endosymbiotic bacteria
D. All bacteria evolved from viruses

Correct Answer: C. Mitochondria have evolved from endosymbiotic bacteria

3. The physical nature of genomes is studied under

A. structural genomics
B. comparative genomics
C. proteo genomics
D. functional genomics

Correct Answer: A. structural genomics

4. The species of bacteria, which possesses 250 genes for lipid biosynthesis is

A. M. genitalium
B. M. tuberculosis
C. E. coli
D. H. influenzae

Correct Answer: B. M. tuberculosis

5. Why the bacterium Treponema pallidum is difficult to culture?

A. Because it requires a great deal of water to reproduce
B. Because it is unable to use carbohydrates as an energy source
C. Because it lacks the genes needed for TCA cycle and oxidative phosphorylation
D. Because it requires extremely low temperature at which water freezes

Correct Answer: C. Because it lacks the genes needed for TCA cycle and oxidative phosphorylation

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