DNA Replication – Section 1

1. Both strands of DNA serve as templates concurrently in

A. replication
B. excision repair
C. mismatch repair
D. none of these

Correct Answer: A. replication

2. Proofreading activity to maintain the fidelity of DNA synthesis

A. occurs after the synthesis has been completed
B. is a function of the 3′-5′ exonuclease activity of the DNA polymerases
C. requires the presence of an enzyme separate from the DNA polymerases
D. occurs in prokaryotes but not eukaryotes

Correct Answer: B. is a function of the 3′-5′ exonuclease activity of the DNA polymerases

3. Which of the following repairs nicked DNA by forming a phosphodiester bond between adjacent nucleotides?

A. Helicase
B. DNA gyrase
C. Topoisomerases
D. DNA ligase

Correct Answer: D. DNA ligase

4. The enzyme that catalyzes the synthesis of DNA is called

A. DNA polymerase
B. DNA gyrase
C. DNA ligase
D. helicase

Correct Answer: A. DNA polymerase

5. Which of the following possesses both 5′-3′ and 3′-5′ exonuclease activity?

A. Kornberg enzyme
B. DNA polymerase III
C. Taq DNA polymerase
D. None of these

Correct Answer: A. Kornberg enzyme

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