1. The HIV virus infects primarily

A. brain cells
B. cells in the immune system
C. red blood cells
D. liver cells

2. Chronic granulomatous disease results from a failure to perform the oxidative burst. This deficiency would be most likely to interfere with

A. CTL killing of viruses
B. dendritic cell activation to become a mature APC
C. infected cell processing of virus peptides
D. macrophage intracellular killing of bacteria

3. Difficulties with somatic gene therapy arise from all of the following except

A. GVHD caused by mature T cells in the transplanted cells
B. inserting a gene so that it will function properly
C. limited life span of more mature hematopoietic cells
D. transducing genetic material into stem cells

4. A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

A. Leu or Ileu
B. His or Pro
C. Tyr or Phe
D. Ser or Thr

5. Retinoblastoma is due to a mutation in a

A. kinase
B. tumor suppressor
C. cyclin
D. viral gene