Transcription and Regulation – Section 1

1. The complex of RNA polymerase, DNA template and new RNA transcript is called

A. transcription bubble
B. replication bubble
C. a translation bubble
D. none of these

Correct Answer: A. transcription bubble
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2. RNA polymerase in prokaryotes has a removable

A. alpha subunit
B. beta subunit
C. both (a) and (b)
D. sigma subunit

Correct Answer: D. sigma subunit
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3. Promoters for tRNAs are located

A. upstream from the start codon
B. downstream from the start codon
C. both (a) and (b)
D. none of these

Correct Answer: B. downstream from the start codon
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4. The binding of lac repressor to DNA could be considered to be analogous to

A. competitive inhibition of an enzyme
B. mixed-type inhibition of an enzyme
C. uncompetitive inhibition of an enzyme
D. allosteric effects in enzyme regulation

Correct Answer: A. competitive inhibition of an enzyme
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5. Rho-dependent termination of transcription in E. coli

A. requires ATP
B. requires about 50 nucleotides of uncomplexed mRNA
C. both (a) and (b)
D. removes mRNA and holoenzyme from the DNA

Correct Answer: C. both (a) and (b)
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