Nucleic Acids – Section 1

1. Because DNA is a highly charged polyanion, its stability to heat denaturation

A. does not depend on hydrophobic interactions
B. increases with increasing salt
C. is independent of G – C content
D. decreases with increasing salt

Correct Answer: B. increases with increasing salt

2. The sugar in RNA is __________ , the sugar in DNA is __________

A. deoxyribose, ribose
B. ribose, deoxyribose
C. ribose, phosphate
D. ribose, uracil

Correct Answer: B. ribose, deoxyribose

3. Nucleoside is a pyrimidine or purine base

A. covalently bonded to a sugar
B. ionically bonded to a sugar
C. hydrogen bonded to a sugar
D. none of the above

Correct Answer: A. covalently bonded to a sugar

4. In gel electrophoresis, what fragments will move most quickly through a gel?

A. Large fragments
B. Small fragments
C. Large genome
D. None of these

Correct Answer: B. Small fragments

5. Which pyrimidine base contains an amino group at carbon 4?

A. Cytosine
B. Thymine
C. Uracil
D. Adenine

Correct Answer: A. Cytosine

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