Microorganisms and Disease – Section 1


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1. Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

A. The possession of a segmented RNA genome
B. A limited number of capsule types
C. The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
D. The ability of the Rotavirus to be transmitted faster

Correct Answer: A. The possession of a segmented RNA genome
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2. Plastic implants can pose a serious nosocomial infection problem because

A. phagocytes have trouble moving on the plastic surface
B. phagocytes have trouble engulfing bacteria embedded in a biofilm
C. infected implants usually have to be surgically removed
D. all of the above

Correct Answer: D. all of the above
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3. A major difference between EHEC and EPEC is

A. EHEC secretes a Shiga-like toxin and EPEC does not
B. EHEC possesses a type III secretion system and EPEC does not
C. EPEC rearranges host cell actin and EHEC does not
D. EPEC passes through the placenta to infect the fetus and EHEC does not

Correct Answer: A. EHEC secretes a Shiga-like toxin and EPEC does not
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4. The nature of the poliovirus gives for oral vaccination (satin vaccine) as part of the eradication program is

A. heat-killed virus
B. live attenuated strains of all three immunological types
C. small dosage of wild-type live viruses
D. formalin-inactivated viruses

Correct Answer: B. live attenuated strains of all three immunological types
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5. Which of the following is true regarding anthrax?

A. Anthrax is caused by a virus
B. Anthrax is highly contagious
C. Inhalation anthrax and cutaneous anthrax are caused by separate strains of Bacillus anthracis
D. Inhalation Anthrax requires infection with a large number of spores

Correct Answer: D. Inhalation Anthrax requires infection with a large number of spores
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