HPLC – Section 1

1. HPLC stands for

A. High Pressure Liquid Chromatography
B. High Performance Liquid Chromatography
C. both (a) and (b)
D. Highly Placed Liquid Chromatography

Correct Answer: C. both (a) and (b)

2. The eluent strength is a measure of

A. solvent adsorption energy
B. solvent absorption energy
C. solvent diffusivity
D. solvent mixing index

Correct Answer: A. solvent adsorption energy

3. HPLC methods include

A. liquid/liquid (partition) chromatography
B. liquid/solid (adsorption) chromatography
C. ion exchange and size exclusion chromatography
D. all of the above

Correct Answer: D. all of the above

4. Column efficiency is measured in terms of number of plates which is

A. inversely related to the square of the peak width
B. directly related to the square of the peak width
C. inversely related to the cube root of the peak width
D. directly related to the square of the peak width

Correct Answer: A. inversely related to the square of the peak width

5. For a typical adsorbent such as silica gel, the most popular pore diameters are

A. 10 and 50 A°
B. 60 and 100 A°
C. 100 and 150 A°
D. 150 and 200 A°

Correct Answer: B. 60 and 100 A°

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