DNA Sequencing, Mutation and Repair – Section 1

6. What was the first eukaryotic chromosome to be sequenced?

A. Yeast chromosome III
B. Yeast chromosome XI
C. Arabidopsis chromosome IV
D. None of these

Correct Answer: A. Yeast chromosome III

7. Which of the following mutations arise without exposure to external agents?

A. Spontaneous mutations
B. Analogous mutations
C. Induced mutations
D. None of these

Correct Answer: A. Spontaneous mutations

8. Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?

A. New strands do not contain cytosine bases
B. New strands are lower in molecular size
C. Old strands are methylated while new strands are not
D. New strands are methylated while old strands are not

Correct Answer: C. Old strands are methylated while new strands are not

9. Which of the following bacterial genome was sequenced first?

A. E. coli
B. S. pneumoniae
C. H. influenzae
D. S. thermophilus

Correct Answer: C. H. influenzae

10. A nonsense mutation may result into

A. an abnormal elongation of a polypeptide
B. a large deletion within the reading frame of a gene
C. a premature termination of the synthesis of a polypeptide
D. modification of mRNA

Correct Answer: C. a premature termination of the synthesis of a polypeptide

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