DNA Sequencing, Mutation and Repair – Section 1

1. Genetic variations are

A. temporary
B. influenced by the environment
C. stable
D. not heritable

Correct Answer: C. stable

2. The mutation which will not affect the length of a protein is,

A. nonsense mutation
B. missense mutation
C. frameshift mutation
D. all of these

Correct Answer: B. missense mutation

3. Changes in which of the following characterizes mutations?

A. Phenotype
B. Genotype
C. Both (a) and (b)
D. None of these

Correct Answer: C. Both (a) and (b)

4. Which of the following(s) is/are steps in excision repair mechanisms?

A. Excision
B. Incision
C. Ligation
D. All of these

Correct Answer: D. All of these

5. The whole-genome shotgun sequencing approach depends primarily on

A. rapidly sequencing thousands of small randomly cloned fragments
B. methodical sequencing a few large cloned fragments of DNA
C. sequencing the bacterial chromosome while it is still intact
D. all of the above

Correct Answer: A. rapidly sequencing thousands of small randomly cloned fragments

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