Translation and Regulation – Section 1

1. Which binding is inhibited by pactamycin?

A. Aminoacyl-tRNA to the A-site of 30S subunit
B. Initiator-tRNA to 30S/40S initiation complexes
C. Peptidyl t-RNA to the 50S subunit
D. Formation of peptide bond in P site

Correct Answer: B. Initiator-tRNA to 30S/40S initiation complexes

2. Which of the following act as the blueprint or template for the process of protein synthesis that takes place on ribosomes?

A. rRNA
B. DNA
C. tRNA
D. mRNA

Correct Answer: D. mRNA

3. Negative regulation of protein synthesis is accomplished by

A. allosteric inhibition
B. the binding of RNA polymerase to the promoter
C. the binding of a repressor to the DNA
D. the binding of a repressor to the RNA polymerase

Correct Answer: C. the binding of a repressor to the DNA

4. Site in the ribosome from which the tRNA donates amino acids to the growing polypeptide chain is

A. P site
B. O site
C. T site
D. A site

Correct Answer: A. P site

5. When was the genetic code completed?

A. 1958
B. 1952
C. 1966
D. 1968

Correct Answer: C. 1966

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