Glycolysis – Section 1

16. Which of the following could act as an uncoupler of electron transport and ATP synthesis?

A. The Fo base-piece of ATP synthase (without the Fl subunit)
B. Dinitrophenol
C. neither (a) nor (b)
D. Both (a) and (b)

Correct Answer: D. Both (a) and (b)
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17. Which of the following is not a mechanism for altering the flux of metabolites through the rate-determining step of a pathway?

A. Allosteric control of the enzyme activity
B. Diffusional coupling between adjacent active sites
C. Genetic control of the enzyme concentration
D. Covalent modification of the enzyme

Correct Answer: B. Diffusional coupling between adjacent active sites
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18. Phosphofructokinase, the major flux-controlling enzyme of glycolysis is allosterically inhibited and activated respectively by

A. ATP and PEP
B. AMP and Pi
C. ATP and ADP
D. Citrate and ATP

Correct Answer: C. ATP and ADP
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19. Which of the following regulates glycolysis steps?

A. Phosphofructokinase
B. Hexose kinase
C. Pyruvate kinase
D. All of these

Correct Answer: D. All of these
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20. During glycolysis, the major energy generating step involves

A. pyruvate kinase
B. phosphoglycerate kinase
C. glyceraldehyde-3 -dehydrogenase
D. Phosphofructokinase

Correct Answer: C. glyceraldehyde-3 -dehydrogenase
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