7. A researcher develops 2 functional mRNA sequences composed of CUC and CUU trinucleotide repeats, respectively. He subsequently incubates these mRNAs in a solution containing functional ribosomes and tRNAs charged with the appropriate amino acids. After several hours, it is found that both mRNA sequences produce polypeptide chains containing leucine repeats. This observed finding is due to which of the following genetic principles?
A. Ambiguity
B. No punctuation
C. Transition
D. Universality
E. Wobble
8. A pharmaceutical researcher develops a new drug that affects bacterial protein synthesis. In an experiment, Escherichia coli is exposed to the drug and serially cultured in media containing tagged nucleotides and amino acids. It is found that the drug inhibits molecules that recognize the highlighted codon in the bacterial mRNA fragment shown in the image below.
5′ — ACG CUA CCA UUG CAA GUU AGC UAA AUA GCG UUC — 3′
Which of the following molecules is the most likely target of this drug?
A. Charged tRNA
B. Elongation factor 2
C. Releasing factor 1
D. snRNP
E. Transcription factor II D
F. Uncharged tRNA
9. A pharmaceutical researcher performs preclinical testing on a novel chemotherapeutic drug. When rat embryos are exposed to this drug during an early stage of organogenesis, they develop severe skeletal malformations. Further genetic analysis reveals that the drug causes mutations in numerous homeobox genes containing highly conserved 180 base pair DNA sequences. The genes affected by this drug most likely code for which of the following proteins?
A. Cell surf ace receptors
B. Cytoplasmic enzymes
C. DNA replication enzymes
D. Structural proteins
E. Transcription regulators
F. Transport proteins