10. A 14-year-old boy experiences severe, prolonged bleeding fol lowing a tooth extraction. He also has a history of multiple episodes of painful joint swelling following minor trauma. His parents have no bleeding problems. Evaluation shows that the patient has an inherited disorder and that one of his parents is a genetic carrier. His older sister, who does not have this condition, is pregnant. She does not know the sex of her child. She asks about the risk that her child will be affected. Which of the following is the best estimate that this child will have the disease?

A. NearO
B. 1/2
C. 1/4
D. 1/8
E. 1/16
F. 1/32

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