Protein Structure – Section 1

6. Marfan’s syndrome is thought to be a mutation affecting

A. hemoglobin synthesis
B. collagen synthesis
C. metabolism of homogentisic acid
D. insufficient thyroid production

Correct Answer: B. collagen synthesis

7. Cyclins are proteins that

A. regulate ability of cells to invade tissue
B. regulate passage from one stage of cell division to another
C. regulate apoptosis of damaged cells
D. none of the above

Correct Answer: B. regulate passage from one stage of cell division to another

8. Over 50% of common cancers are associated with damage to a protein, p53. This protein

A. is a cyclin
B. is a tumor supressor
C. is an oncogene
D. regulates apoptosis

Correct Answer: B. is a tumor supressor

9. Protein folding is

A. automatic, mediated by the protein itself
B. mediated by other proteins called chaperones
C. mediated by the ribosomes
D. none of the above

Correct Answer: B. mediated by other proteins called chaperones

10. Sickle cell disease is due to

A. a mutation in the beta chain of Hb
B. a mutation in the alpha chain of Hb
C. infection with a parasite
D. none of the above

Correct Answer: A. a mutation in the beta chain of Hb

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