Monoclonal Antibodies – Section 1

16. The antigen-specific lymphocytes can be immortalized by which of the following method?

A. Transfection with tumor-derived DNA
B. Hybridization with a suitable lymphoid tumor cell
C. Transformation following infection by Epstein-Barr virus (EB V)
D. All of the above

Correct Answer: D. All of the above

17. A cytokine that stimulates the activity of B and T cells is

A. lymphotoxin
B. interleukin-2
C. interleukin-1
D. all of these

Correct Answer: B. interleukin-2

18. Which type of cell actually secrets antibodies?

A. plasma cells
B. T cells
C. macrophages
D. dendritic cells

Correct Answer: A. plasma cells

19. Which of the following is correct?

A. rabbits do not make myelomas whereas mice are unable to synthesize antibodies
B. rabbits do not make myelomas whereas mice are able to synthesize antibodies
C. rabbits make myelomas whereas mice are unable to synthesize antibodies
D. rabbits make myelomas whereas mice are able to synthesize antibodies

Correct Answer: A. rabbits do not make myelomas whereas mice are unable to synthesize antibodies

20. The Ig locus is about

A. 2/3rd of all hybridomas
B. l/3rd of all hybridomas
C. l/2nd of all hybridomas
D. 1/4th of all hybridomas

Correct Answer: A. 2/3rd of all hybridomas

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