Enzymes and Kinetics – Section 1

16. Which of the following common drugs is not a specific enzyme inhibitor?

A. Iodine
B. Methotrexate
C. Sulfanilamide
D. Penicillin

Correct Answer: A. Iodine

17. The enzyme inhibition can occur by

A. reversible inhibitors
B. irreversible inhibitors
C. Both (a) and (b)
D. None of these

Correct Answer: C. Both (a) and (b)

18. In a Lineweaver-Burk Plot, a competitive inhibitor shows which of the following effect?

A. It moves the entire curve to the right
B. It moves the entire curve to left
C. It changes the x-intercept
D. It has no effect on the slope

Correct Answer: C. It changes the x-intercept

19. Which of the following statements is not true?

A. Enzymes are proteins that bind to specific substrates and increase the velocity of reactions involving those substrates
B. Enzymes function by overcoming the activation energy barrier of a reaction
C. Enzymes make thermodynamically favorable reactions to proceed; they cannot make unfavorable reactions to occur
D. Enzymes only function when they are in intact cells

Correct Answer: D. Enzymes only function when they are in intact cells

20. Non-competitive inhibitor of an enzyme-catalyzed reaction

A. decreases Vmax
B. binds to Michaelis complex (ES)
C. both (a) and (b)
D. can actually increase reaction velocity in rare cases

Correct Answer: C. both (a) and (b)

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