DNA Structure and Replication – Section 2

26. Which of the following species lack a ‘classical’ histone H1?

A. Saccharomyces cerevisiae
B. Strongylocentrotus purpuratus
C. Xenopus laevis
D. Arabidopsis thaliana

Correct Answer: A. Saccharomyces cerevisiae

27. Which of the following is correct?

A. Replication starts at a single origin
B. Replication is bidirectional
C. Replication is semi conservative
D. All of the above

Correct Answer: D. All of the above

28. The size of a linear DNA fragment in a gel can be estimated by

A. fluorescence in UV light
B. the sedimentation coefficient
C. the time it takes the gel to run
D. comparison with a molecular weight standard such as Hind III digested phage lambda

Correct Answer: D. comparison with a molecular weight standard such as Hind III digested phage lambda

29. Which of the following are short nucleotides strands made by DNA polymerase working in the opposite direction of the replication fork?

A. Leading strands
B. Okazaki fragments
C. Primers
D. Lagging strand

Correct Answer: B. Okazaki fragments

30. Which of these drugs bind to DNA and cuts it, producing hydroxyl radicals?

A. Bleomycin
B. Erythromycin
C. Tunicamycin
D. All of these

Correct Answer: A. Bleomycin

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