Antimicrobial Chemotherapeutic Agents – Section 1


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6. Chemotherapeutic agents must

A. prevent/destroy the activity of a parasite
B. leave unaltered the host’s natural defense mechanisms
C. be able to come in contact with the parasite by penetrating the cells
D. all of the above

Correct Answer: D. all of the above
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7. Novobiocin can be used against

A. gram +ve Staphylococci
B. gram -ve Meningococci & Gonococci
C. Haemophilus
D. all of these

Correct Answer: D. all of these
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8. Interference mechanism of ciprofloxacin and norfloxacin is due to their action on

A. cell wall synthesis
B. cell membrane function
C. DNA function
D. protein synthesis

Correct Answer: C. DNA function
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9. By which of the following means antifungal chemotherapeutic agents may affect fungi?

A. Interfere with nuclear division by preventing the aggregation of microtubules needed for mitosis
B. Interfere with normal nucleic acid synthesis
C. Interfere with ergosterol biosynthesis and thus alter the structure of the cytoplasmic membrane as well as the function of several membrane-bound enzymes like those involved in nutrient transport and chitin synthesis
D. all of these

Correct Answer: D. all of these
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10. Which of the following methods would be most appropriate for sterilizing an antibiotic solution?

A. Dry heat sterilization
B. Microfiltration
C. Autoclaving
D. Desiccation

Correct Answer: B. Microfiltration
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